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Browsing by Subject "LANA"
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Dynamics of KSHV gene expression during de novo infection and the role of LANA in immune modulation
(2015)Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic human herpes virus that has been linked to the development of multiple malignancies including Kaposi's sarcoma, primary effusion lymphoma, and multicentric ... -
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KSHV Genome Replication and Maintenance
(2016)Kaposi's sarcoma associated herpesvirus (KSHV) or human herpesvirus 8 (HHV8) is a major etiological agent for multiple severe malignancies in immune-compromised patients. KSHV establishes lifetime persistence in the infected ... -
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Modulation of Kaposi's Sarcoma-associated Herpesvirus (KSHV/HHV8) origin-dependent DNA replication by K-bZIP, K-Rta, and LANA
(2009)There are eight Kaposi Sarcoma-associated Herpesvirus (KSHV) viral-encoded proteins that are necessary for lytic origin-dependent DNA replication. Six of the eight proteins have a high level of homology to other herpesvirus ... -
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Regulation of Replication and Translation During KSHV Life Cycle
(2019)Kaposi’s sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8 (HHV-8), is a γ2-lymphotropic virus of the herpesvirus family that establishes asymptomatic infections in immunocompetent hosts but causes ... -
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Regulation of Viruses Through Internal G-quadruplex Stabilization
(2023)Kaposi's sarcoma-associated herpesvirus (KSHV) is a gamma-herpesvirus implicated as the causative agent for several malignancies, including Kaposi's sarcoma, primary effusion lymphoma, and certain forms of multicentric ...