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Browsing Electrical and Biomedical Engineering by Author "Cheng, Qingsu"
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BioSig3D: High Content Screening of Three-Dimensional Cell Culture Models
Bilgin, Cemal C.; Fonteney, Gerald; Cheng, Qingsu; Chang, Hang; Han, Ju; Parvin, Bahram (2016)BioSig3D is a computational platform for high-content screening of three-dimensional (3D) cell culture models that are imaged in full 3D volume. It provides an end-to-end solution for designing high content screening assays, ... -
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Buckyballs conjugated with nucleic acid sequences identifies microorganisms in live cell assays
Cheng, Qingsu; Parvin, Bahram (2017)Rapid identification of bacteria can play an important role at the point of care, evaluating the health of the ecosystem, and discovering spatiotemporal distributions of a bacterial community. We introduce a method for ... -
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Functionalized Buckyballs for Visualizing Microbial Species in Different States and Environments
Cheng, Qingsu; Aravind, Ashwin; Buckley, Matthew; Gifford, Andrew; Parvin, Bahram (Scientific Reports, 2015)To date, in situ visualization of microbial density has remained an open problem. Here, functionalized buckyballs (e.g., C60-pyrrolidine tris acid) are shown to be a versatile platform that allows internalization within a ... -
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Stiffness of the microenvironment upregulates ERBB2 expression in 3D cultures of MCF10A within the range of mammographic density
Cheng, Qingsu; Bilgin, Cemal C.; Fonteney, Gerald; Chang, Hang; Henderson, Matthew; Han, Ju; Parvin, Bahram (2016)The effects of the stiffness of the microenvironment on the molecular response of 3D colony organization, at the maximum level of mammographic density (MD), are investigated. Phenotypic profiling reveals that 3D colony ...